尊龙凯时 - 人生就是搏!-z6com

研究成果

英文

2021

1.XH Fu, MK Xu (Corresponding author), TT Li, YS Li, HW Zhang, CG Zhang. The improved expression and stability of zearalenone lactonohydrolase from Escherichia coli BL21 (DE3). Applied Biochemistry and Microbiology.2021. 571):79-85.

2.Yang Tingting, Zhang Huiwen, Wang Jian, Li Xinyu*, Li Xu, Su Zhencheng. High bioremediation potential of strain Chenggangzhangella methanolivorans CHL1 for soil polluted with metsulfuron-methyl or tribenuron-methyl in a pot experiment. Environmental Science and Pollution Research, 2020, 28):4731-4738.

3.Yunhe Ban, Xiang Li, Yuqi Li, Xu Li, Xiujuan Wang, Zhencheng Su*, Huiwen Zhang. Comparative analysis of paddy straw-degrading consortia in China using high-throughput sequencing. Applied Soil Ecology, 2021, 167: 104077

2020

4.Wang, Huanhuan; Li, Xiang; Li, Xu; Wang, Jian; Li, Xinyu; Guo, Qiucui; Yu, Zhixiong; Yang, Tingting; Zhang, Huiwen. Long-term no-tillage and different residue amounts alter soil microbial community composition and increase the risk of maize root rot in northeast China. Soil & Tillage Research 2020,196,104452.

5.Wang, Huanhuan; Guo, Qiucui; Li, Xiang; Li, Xu; Yu, Zhixiong; Li, Xinyu; Yang, Tingting; Su, Zhencheng; Zhang, Huiwen Zhang, Chenggang. Effects of long-term no-tillage with different straw mulching frequencies on soil microbial community and the abundances of two soil-borne pathogens. Applied Soil Ecology 2020,148,103488.

6.Yubo Song, Mingkai Xu, Yongqiang Li, Yansheng Li, Wu Gu, Gulinare Halimu, Xuanhe Fu, Huiwen Zhang, Chenggang Zhang. An iRGD peptide fused superantigen mutant induced tumor-targeting and T lymphocyte infiltrating in cancer immunotherapy, International Journal of Pharmaceutics, 2020,586,119498.

7.Xuanhe Fu; Mingkai Xu; Huiwen Zhang; Yongqiang Li; Yansheng Li; Chenggang Zhang, Staphylococcal enterotoxin C2 mutant-directed fatty acid and mitochondrial energy metabolic programmes regulate CD8+ T cell activation. The Journal of Immunology, 2020, 205 (8): 2066-2076

8.Li Xu, Wang Huanhuan, Li Xiang, Li Xinyu*, Zhang Huiwen. Distribution characteristics of fungal communities with depth in paddy fields of three soil types in China. Journal of Microbiology, 2020, 58:279–287.

9.Yu Zhixiong, Zhang Huiwen, Fu Xuanhe, Li Xu, Guo Qiucui, Yang Tingting, Li Xinyu *. Immobilization of esterase SulE in cross-linked gelatin/chitosan and its application in remediating soils polluted with tribenuron-methyl and metsulfuron-methyl. Process Biochemistry, 2020, 98: 217–223.

2019

10.MK Xu, GLNR Halimu, QR Zhang, YB Song, XH Fu, YQ Li, YS Li, HW Zhang. 2019. Internalization and toxicity: A preliminary study of effects of nanoplastic particles on human lung epithelial cell. Science of the Total Environment. https://doi.org/10.1016/j.scitotenv.2019.133794.

11.Xu Li, Huanhuan Wang, Xiang Li, Xinyu Li*, Huiwen Zhang. Shifts in bacterial community composition increase with depth in three soil types from paddy elds in China. Pedobiologia - Journal of Soil Ecology. 2019,77:150589.

2018

12.Songyuan Yao, Mingkai Xu, Yansheng Li, Libao Zhou, Hui Liao, Huiwen Zhang, Chenggang Zhang; Staphylococcal enterotoxin C2 stimulated the maturation of bone marrow derived dendritic cells via TLR-NFκB signaling pathway, Experimental Cell Research, Volume 370, Issue 2, 2018, Pages 237-244.

13.Songyuan Yao, Yongqiang Li, Qianru Zhang, Huiwen Zhang, Libao Zhou, Hui Liao, Chenggang Zhang, Mingkai Xu; Staphylococcal enterotoxin C2 as an adjuvant for rabies vaccine induces specific immune responses in mice, Pathogens and Disease, Volume 76, Issue 5, 1 July 2018, fty049.

14.Jian Wang, XinYu Li, Xu Li, Huan Huan Wang, ZhenCheng Su, Xiujuan Wang, Huiwen Zhang*. Dynamic changes in microbial communities during the bioremediation of herbicide (chlorimuron-ethyl and atrazine) contaminated soils by combined degrading bacteria. PLOS ONE (2018) 13(4): e0194753.

15.Xinyu Li, Jian Wang, Shaopeng Zhang, Huanhuan Wang, Xiang Li, Xu Li*, Huiwen Zhang. Distribution of fungal endophytes in roots of Stipa krylovii across six vegetation types in grassland of northern China,Fungal Ecology,2018,31: 47-53.

16.Xuanhe Fu, Mingkai Xu*, Yubo Song, Yongqiang Li, Huiwen Zhang, Jinghai Zhang, Chenggang Zhang. Enhanced interaction between SEC2 and TCR Vβ induces MHC II-independent activation of T cells via PKCθ/NF-?B  and IL-2R/STAT5 signaling pathways. J. Biol. Chem. 2018, 293(51):19771-19784 .

2017

17. Li XY, Sun J, Wang HH, Li X, Wang J, Zhang HW. Changes in the soil microbial phospholipid fatty acid profile with depth in three soil types of paddy fields in China. Geoderma.2017, 290: 69-74.

18.Huanhuan Wang, Xu Li, Xiang Li, Xinyu Li*, Jian Wang, Huiwen Zhang,Changes of microbial population and N-cycling function genes with depth in three Chinese paddy soils, PLoS ONE 12(12): e0189506.

19.Xuanhe Fu, Mingkai Xu, Songyuan Yao, Huiwen Zhang, Chenggang Zhang, Jinghai Zhang. Staphylococcal enterotoxin C2 mutant drives T lymphocyte activation through PI3K/mTOR and NF-?B signaling pathways. Toxicol. Appl. Pharmacol. 2017. 333:51-59.

2016

20.Guojun Zhang, Mingkai Xu, Yubo Song, Zhencheng Su, Huiwen Zhang, Chenggang Zhang. TNF-α produced by SEC2 mutant (SAM-3)-activated human T cells induces apoptosis of HepG2 cells. Applied Microbiology AND Biotechnology ,2016,100:2677–2684.

21.Li-Qiang YangLan LiuNimaichand SalamMin XiaoChang-Jin KimWael N. HozzeinDong-Jin ParkWen-Jun Li, Hui-Wen Zhang.Chenggangzhangella methanolivorans gen. nov., sp. nov., a member of the family Methylocystaceae, transfer of Methylopila helvetica Doronina et al. 2000 to Albibacter helveticus comb. nov. and emended description of the genus Albibacter. International journal of systematic and evolutionary microbiology, 2016, 66: 2825-2830.

22.Guojun Zhang, Mingkai Xu, Huiwen Zhang, Yubo Song, Jian Wanga, Chenggang Zhang. Up-regulation of granzyme B and perforin by staphylococcal enterotoxin C2 mutant induces enhanced cytotoxicity in Hepa1–6 cells. Toxicology and Applied Pharmacology. 313:1-9.

2015

23.Yang L, Li X, Li X, et al. Microbial Community Dynamics during the Bioremediation Process of Chlorimuron-Ethyl-Contaminated Soil by Hansschlegelia sp. Strain CHL1.[J]. Plos One, 2015, 10.

24.Liqiang Yang, Xinyu Li, Xu Li, et al. Improved stability and enhanced efficiency to degrade chlorimuron-ethyl by the entrapment of esterase SulE in cross-linked poly (γ-glutamic acid)/gelatin hydrogel.[J]. Journal of Hazardous Materials, 2015, 287c:287–295.

2014

25.Jianfei Xie, Yongshan Zhao, Huiwen Zhang, Zhiyuan Liu, Zongyun Lu. Improving methyl parathion hydrolase to enhance its chlorpyrifos-hydrolysing efficiency. 2014, 58(1):53-59 

26.Liu, Y. L., Xu, M. K., Li, X., Sun, J., Zhang, C. G. and Zhang, H. W. The construction of a bifunctional fusion protein consisting of SEC2 and EGFP. 2014, DOI: 10.1002/bab.1203.

27.Jianfei Xie, Huiwen Zhang, Xu Li, Yuanliang Shi. Entrapment of Methyl ParathionHydrolase in CrossLinked Poly (γglutamic acid)/Gelatin Hydrogel. Biomacromolecules. 2014, 15: 690-697.

2013

28.Jingjing Wang, Huiwen Zhang, Xiaoli Zhang, Shenghong Qin , Huanbo Tan, Xinyu LI. Effects of long-term chlorimuron-ethyl application on the diversity and antifungal activity of soil Pseudomonas spp. In a soybean field in Northeast China..Ann Microbiol 2013( 63):335–341

29.Huanbo Tan, Mingkai Xu, Xinyu Li, Huiwen Zhang, Chenggang Zhang. Effects of chlorimuron-ethyl application with or withour urea fertilization on soil ammonia-oxidizing bacteria and archaea.Journal of Hazardous Materials.2013(260):368-374

30.Xinyu Li, Xu Li, Jian Wang, Xiujuan Wang, Jian Sun, Zhencheng Su, Huiwen Zhang, and Peijun Li. Profiles of Mycobacterium communities under polycyclic aromatic hydrocarbon contamination stress in the Shenfu Irrigation Area, northeast China. Can. J. Microbiol. (2013)59: 694–700

31.Zhencheng Su ,Jian Wang, Xu Li,Xinyu Li  ,Huiwen Zhang , Peijun Li.The effect of polycyclic aromatic hydrocarbon contamination on distribution of the Sphingomonas community in the Shenfu irrigation area of Northeast China. Ann Microbiol (2013) 63:1005–1012.

32.Xinyu Li, Ye Deng, Qi Li, Caiyan Lu, Jingjing Wang, Huiwen Zhang, Jianguo Zhu, Jizhong Zhou, and Zhili He .Shifts of functional gene representation in wheat rhizosphere microbial communities under elevated ozone. ISME Journal (2013) 7, 660–671

33.Zhencheng Su ,Jian Wang, Xu Li,Xinyu Li  ,Huiwen Zhang , Peijun Li.The effect of polycyclic aromatic hydrocarbon contamination on distribution of the Sphingomonas community in the Shenfu irrigation area of Northeast China. Ann Microbiol (2013) 63:1005–1012.

34.Xinyu Li, Ye Deng, Qi Li, Caiyan Lu, Jingjing Wang, Huiwen Zhang, Jianguo Zhu, Jizhong Zhou, and Zhili He .Shifts of functional gene representation in wheat rhizosphere microbial communities under elevated ozone. ISME Journal (2013) 7, 660–671

35.Jian Wang, FengMei Li, XuLi, XiuJuanWang, XinYuLi, ZhenCheng Su, HuiWen Zhang, ShuHai Guo. Effects of electrokinetic operation mode on removal of polycyclic aromatic hydrocarbons (PAHs), and the indigenous fungal community in PAH-contaminated soil. Journal of Environmental Science and Health, Part A (2013) 48 , 1677–1684.

36.Xiaoli Zhang, Xu Li, Chenggang Zhang, Xinyu Li, Huiwen Zhang. Responses of soil nitrogen-fixing, ammonia-oxidizing and denitrifying bacterial communities to long-term chlorimuron-ethyl stress in a continuously cropped soybean field in Northeast China. Ann. Microbiol. (2013)63:1619-1627.

37.Yanli Liu, Mingkai Xu, Huiwen Zhang, Xu Li, Zhencheng Su, Chenggang Zhang.SEC2-induced superantigen and antitumor activity is regulated through calcineurin. Applied Microbiology and Biotechnology. 201397:695-9703

2012

38.Y.Liu, M. Xu, Z.Su, Y. Cai, G.Zhang and H. Zhang .Increased T-cell stimulating  activity by mutated SEC2 correlates with its improved antitumour potency. Letters in Applied Microbiology.2012,55:362-369

39.J.J.Wang, X.Y.Li, A.N.Zhu, X.K.Zhang, H.W.Zhang, W.J.Ling. Effects of tillage and residue management on soil microbial communities in North China. PLANT SOIL ENVIRON., 58, 2012 (1): 28–33

40.Jingjing Wang, Huiwen Zhang, Xiaoli Zhang, Shenghong Qin , Huanbo Tan, Xinyu LI. Effects of long-term chlorimuron-ethyl application on the diversity and antifungal activity of soil Pseudomonas spp. In a soybean field in Northeast China..Ann Microbiol (2013) 63:335–341

2011

41.Xiaoli Zhang, Xu Li, Chengang Zhang , Xinyu Li, Huiwen Zhang. Ecological risk of long-term chlorimuron-ethyl application to soil microbial community: an in situ investigation in a continuously cropped soybean field in Northeast China.Environ Sci Pollut Res .2011,18:407-415

42.Mingkai Xu, Xiaogang Wang, Yongming Cai, Huiwen Zhang, Hongli Yang, Changxiao Liu, Chenggang Zhang. An engineered superantigen SEC2 exhibits promising antitumor activity and low toxicity. Cancer Immunol Immunother.2011,60:705-713

43.Hongbo Wang, Junyi Zhou, Mingkai Xu, Huiwen Zhang and Chenggang Zhang.The functional roles of the residue tyrosine at position 26 in staphylococcal enterotoxin C2 .African Journal of Microbiology Research Vol. 5(16), pp. 2329-2337, 18 August, 2011

2010

44.Minna Wu, Xinyu Li, Huiwen Zhang, Yinghui Cai and Chenggang Zhang. Effects of methamidophos on the community structure, antagonism towards Rhizoctonia solani, and phlD diversity of soil Pseudomonas. Journal of Environmental Science and Health Part B (2010)45,222-22

45.ZHANG Jing , ZHANG Hui-Wen, ZHANG Cheng-Gang .Effect of groundwater irrigation on soil PAHs pollution Abatement and Soil Microbial Characteristics :A Case Study in Northeast China. Pedosphere.2010,20(5):557-567

46.Li Xinyu, Su Zhencheng, Li Xu, Zhang Chenggang, Zhang Huiwen. Assessing the effects of acetochlor on soil fungal communities by DGGE and clone library analysis, Ecotoxicology, 2010, 19:1111-1116

2009

47.Xiaogang Wang · Mingkai Xu · Huiwen Zhang ·Jie Liu · Xu Li · Chenggang Zhan(2009), Enhancement of superantigen activity and antitumor response of staphylococcalenterotoxin C2 by site-directed mutagenesis Cancer Immunol Immunother  58:677–686

48.Xiaogang Wang & Huiwen Zhang & Mingkai Xu & Changxiao Liu & Chenggang Zhang(2009),Biological analysis of the deletion mutants of Staphylococcal enterotoxin C2. Appl Microbiol Biotechnol83:1077–1084

49.Xiaogang Wang & Mingkai Xu & Yongming Cai & Hongli Yang & Huiwen Zhang & Chenggang Zhang(2009)Functional analysis of the disulphide loop mutant of staphylococcal enterotoxin C2Appl Microbiol Biotechnol  82:861–871

50. Xiaogang Wang,1,3 Huiwen Zhang,1 Mingkai Xu,1 Yongming Cai,2Changxiao Liu,2 Zhencheng Su1 and Chenggang Zhang1,2009,Biological characterization of the zinc site coordinating histidine residues of staphylococcal enterotoxin C2Microbiology , 155, 680–686

2008

51.Li Xinyu, Zhang Huiwen, Wu minna Su Zhencheng and Zhang Chenggang, Impact of acetochlor on ammonia-oxidizing bacteria in microcosm soils. Journal of Environmental Sciences, 2008, 20: 1126–1131.

52.Li Xinyu, Zhang Huiwen, Wu Minna, Zhangyan and Zhang Chenggang, Effects of methanidophos on soil fungi community in microcosms by plate count, DGGE and clone library analysis. Journal of Environmental Sciences, 2008, 20 (5).619-625

53.WU Min-na, Zhang Hui-wen, Li Xin-yu, Su Zhen-cheng, Zhang Cheng-gang, Soil fungistasis and its relations to soil microbial composition and diversity: A case study of a series of soils with different fungistasis.  Journal Environmental of Sciences, 2008, 20(7): 871-877.

54.Yan Zhang, Huiwen Zhang, Xinyu Li, Zhencheng Su, Chenggang Zhang. The cadA gene in cadmium-resistant bacteria from cadmium-polluted soil in the Zhangshi Area of Northeast China. Current Microbiology, 2008, 56(3):236-239.

55.Yan Zhang, Huiwen Zhang, Zhencheng Su, Chenggang Zhang. Soil Microbial Characteristics under Long-term Heavy Metals Stress: A Case Study in Zhangshi Wastewater Irrigation Area, Shenyang. Pedosphere, 2008,18(1):1-10.

56.Wang XG, Xu MK, Zhang HW, Liu J, Li X, Zhang CG. (2008) Enhancement of superantigen activity and antitumor response of Staphylococcal enterotoxin C2 by site-directed mutagenesis. Cancer Immunol Immunother. DOI 10.1007/s00262-008-0590-6.

57.Wang XG, Xu MK, Cai YM, Yang HL, Zhang HW, Zhang CG. (2008) Functional analysis of the disulphide loop mutant of Staphylococcal enterotoxin C2. Appl Microbiol Biotechnol. DOI 10.1007/s00253-008-1800-z

58.Yan Zhang,Xiaoli Zhang, Huiwen Zhang, Qiang He, Qixing Zhou, Zhencheng Su, Chenggang Zhang. Responses of Soil Bacreria to Long-Term and Short-Term Cadmium Stress as Revealed by Mirobial Community Analysis,Bull Envrion Contam Tosicol,DOI 10.1007/s00128-008-9613-4

2007-2003

59.Su Zhen-cheng, Zhang Hui-wen, Li Xin-yu, Zhang Qin, Zhang Cheng-gang, Toxic effects of acetochlor, methamidophos and their combination on nifH gene in soil. Journal of Environmental Sciences, 2007 (19):864-873.

60.XU Ming-Kai, ZHANG Cheng-Gang, ZHANG Hui-Wen, ZHOU Ya-Feng, ZHANG Xian-En, LIU Li. Fusion Immunotoxin Anti-HER-2-scFv-SEC2 Expressed in E.coli With an Improved Expression Vector pASK75-EX: Its Construction and Functioning. Progress in Biochemistry and Biophysics, 2006,33(8):781~788.

61.Zhang Huiwen, Zhou Qixing, Zhang Qianru et al. 2005,Impacts of Methamidophos, copper, and their combinations on bacterial community structure and function in black soil, Science in China vol.48 Supp

62.Li, X. Y., Zhang, H. W., Zhou, Q. X., Su, Z. C. and Zhang, C. G. 2005, Effects of acetochlor and methamidophos on fungal communities in black soils .Pedosphere. 15(5):646-652.

63.H. Zhang, Q. Zhang, Q, Zhou, C. Zhang, 2003. Binary-Joint Effects of Acetochlor, Methamidophos, and Copper on Soil Microbial Population. Bulletin Environmental Contamination and Toxicology, 71(4):746-754

中文

2020

1. , 王欢欢, 郭秋翠, , 李新宇*, 张惠文. 玉米茎腐病病原禾谷镰孢拮抗菌筛选及分子鉴定.[J].玉米科学, 2020, 28(5): 169-175.(通讯作者:李新宇)

2.班允赫,  , 李新宇, 王秀娟, 苏振成, 张惠文. 利用高通量测序技术对水稻秸秆中、低温降解菌系的比较分析.[J]. 微生物学杂志,2020,405):7-17(通讯作者:苏振成)

3.徐明恺,张致淳,张惠文,张成刚.超级抗原在肿瘤免疫治疗中的应用.[J].微生物学杂志,2020,40(5):1-6

2019

4.班允赫, 李旭, 李新宇, 王秀娟, 王健, 苏振成, 张惠文. 降解菌系和助腐剂对不同还田方式下水稻秸秆降解特征的影响.[J].生态学杂志, 2019, 38(10): 2982-2988.

2018

5.李永强,姚崧源,李延胜,徐明恺,张惠文,张成刚.靶向HER2CAR-T细胞构建与抗肿瘤活性的体外分析.[J].生物工程学报,2018,34(05):731-742

2016

6.PAHs污染土壤的物理强化修复过程中土壤细菌的响应.宋宇,王健,苏振成, 张惠文. 生态学杂志, 2016,35(6):1547-1552.

2015

7. , 杨丽强, , 李新宇,张惠文. 不同草原类型针茅根部可培养内生细菌群落结构及其功能.[J].生态学杂志,2015,34(11):3101-3110.

8.孟北乾,张惠文,张国俊,徐明恺,李旭,张成刚。豚鼠和BLAB/c小鼠对SEC2超抗原作用敏感性的比较. [J].生物技术通报,2015,31(9):224-231.

2014

9.晏培,王秀娟,孙健,宋宇,张惠文,李新宇. 臭氧浓度升高对不同品种小麦根际细菌种群的影响.[J].生态学杂志,2014, 33(4) 1015-1020.

10.张少鹏,胥婷,杨丽强,宋宇,李新宇,张惠文.不同草原类型针茅根部内生真菌群落结构.[J].应用生态学报。2014,25(12):2475-3482.

2013

11.张国俊,徐明恺,孙健,李洪义,杨宏丽,张惠文,张成刚.增强型金黄色葡萄球菌肠毒素C2突变体及其超抗原活性.[J].生物工程学报,2013, 29(6): 803813.

12.刘彦礼, , 苏振成, 徐明恺, 张惠文.动力学模型在荧光定量PCR数据处理中的优势.[J].生物技术通报. . 2013,2:157-162.

13.刘彦礼,张惠文,徐明恺, ,张成刚.钙调神经磷酸酶对金黄色葡萄球菌肠毒素C2超抗原活性的作用.[J].中国生物制品学杂.2013,26(10):1413-1417.

2012

14.周隽逸,李旭,张怡轩,徐明恺.肠毒素C2蛋白C,N末端对其活性的影响.[J].生物技术,2012,22(1):34-38

15.李旭,马福海,王秀娟,孙健,张惠文.大豆根腐病生防菌KJB04-11的鉴定及其产生的脂肽类抗生素.[J].生态学杂志,2012,316):1400-1407

16.秦胜红,李新宇,李旭,谢建飞,苏振成,张惠文.不同土壤细菌种群结构对氯嘧璜隆胁迫的响应及降解菌系的获得.[J].生态学杂志,2012,31(7):1724-1732

17.谭焕波,李新宇,张惠文,李旭,徐明恺.氯嘧磺隆与尿素对土壤微生物生物量碳、氮及无机氮的影响.[J].应用生态学报,2012,23(8):2219-2224

18.王敬敬,李新宇,徐明恺,苏振成,李旭,孙健,张惠文.保护性耕作对土壤光合细菌和II型甲烷氧化菌的影响.[J].生态学杂志,2012,31(9):1-10.

19.谭焕波, 张国俊, 徐明恺, 张惠文.纳豆激酶基因的克隆表达及活性分析.[J].食品工业科技.2012,(18):195-198.

20.张国俊,徐明恺,邹谨,周隽逸,张惠文.活性增强的SEC2截短突变蛋白的构建及其生物活性研究.[J].生物技术,2012, 22(6):31-35.

2011

21.王爽,张惠文,叶淑红,徐明恺。还原型谷胱甘肽高产菌株的初筛及其提取工艺优化.[J].生物技术,2011,21(3):76-82

22.胡凤钗,李新宇,苏振成,王秀娟,张惠文,孙军德.三株降解芘的戈登氏菌鉴定及其降解能力.[J].应用生态学报,2011,22(7):1857-1862

23.胡凤钗,苏振成,孙健,李旭,张惠文,孙军德.高效芘降解菌N12 的分离鉴定与降解特性.[J]. 应用生态学报,2011,22(6):1566-1572

24.王洪波,李洪义,孙健,张惠文,徐明恺. 肠毒素C2Met24对其超抗原活性无重要作用.[J].生物技术,2011,21(4):67-70

2010

25.阮晓东,张晓黎,杨瑞珍,苏振成,张惠文.江苏云台山野生珍惜濒危重要植物初步研究.[J].中国野生植物资源.2010,29(1):21-24

26.张旭,张惠文,徐明恺.Nisin(乳链菌肽)高产菌选育研究进展.[J].食品研究与开发.2010,31(1):175-177。)

27.冯永宁,张惠文,徐明恺,徐威,张成刚.金葡菌肠毒素促鸡淋巴细胞增殖及增强疫苗效价的初步探讨[J].生物技术通报,2010(9):165-168.

28.张旭,张惠文,徐明恺.基因组重排技术选育乳链菌肽高产菌株[J].中国生物制品学杂志,2010,23(10):1065-1073

2009

29.阮晓东,张惠文,孙冬雪,蔡颖慧,李新宇.油松阔叶混交林不同层次优势植被根区土壤真菌的群落结构,东北林业大学学报,2009,375:48-50

30.阮晓东,张惠文,蔡颖慧,王振宇,苏振成.短刺小克银汉霉菌丝球对孔雀绿的吸附研究,水处理技术,2009,358:50-54

31.阮晓东,张惠文,李新宇,徐明恺,李旭,张晓黎,苏振成.短刺小克银汉霉对偶氮染料刚果红的脱色.尊龙凯时人生就是搏z6com研究生院学报2009,263:330-336

32.阮晓东,张惠文,蔡颖慧,王艺纯,孙冬雪,黄婷.微生物在中药生物转化中的应用,[J].中草药,2009,140:149-152

33.蔡颖慧,张惠文,苏振成,张晓黎,李新宇.敌敌畏降解菌的分离鉴定及降解特性研究[J].生物技术,2009,19(2):59-62

34.张旭,张惠文,徐明恺,苏振成,李新宇.超声波诱变选育乳链菌肽(Nisin)高产菌株.[J].生物技术,2009,19(6):20-22

2008

35.阮晓东,孙冬雪,李新宇,张惠文.江苏省云台山7种野生中草药植物根区土壤真菌多样性研究[J].江苏农业学报,2008,24(5):629-633

36.阮晓东,张晓黎,张惠文.食用菌液体菌种的发展与应用[J].辽宁农业科学,2008(1):32-35

37.罗永平,张惠文,王小刚,徐明恺,苏振成,张成刚. 抗菌肽CP10A在大肠杆菌中的融合表达. 中国生物工程杂志;2008 28 (7): 105-109

38.吕英杰,张惠文,吕淑霞,高嵩峰.红树莓干酒酿造菌种筛选及工艺优化,酿酒,2008,352:80-84

39.李新宇,张惠文,吴敏娜,张勤,张成刚.乙草胺、甲胺磷及其复合对土壤真菌种群的毒性效应[J].农业环境科学学报,2008,27(5):1842-1847

40.吴敏娜,张惠文,李新宇,张彦,苏振成 张成刚.土壤抑真菌作用与细菌群落结构的关系[J].应用生态学报,2008,19(7):1574-1578

41.吴敏娜,张惠文,李新宇,张彦,苏振成 张成刚.乙草胺胁迫对土壤真菌拮抗功能和假单胞菌以及芽胞杆菌群落结构的影响[J].农业环境科学学报,2008,27(3):926-931

42.张晶,张惠文,李新宇,张成刚,赵光明.多环芳烃胁迫下稻田土壤细菌及分支杆菌种群多样性研究[J].中国生态农业学报,2008,16(2):405-410

43.张晶,张惠文,张勤,张成刚.长期石油污水灌溉对东北旱田土壤微生物生物量及土壤酶活性的影响[J].中国生态农业学报,2008,16(1):67-70

2007

44.吴敏娜,张惠文,李新宇,苏振成,张成刚.提取北方土壤真菌DNA的一种方法[J].生态学杂志,2007,26(4):611-616

45.王小刚,张惠文,苏振成,徐明恺,罗永平,张成刚.SEB金黄色葡萄球菌α-溶血毒素基因缺失菌株的构建[J]. 中国生物工程杂志,2007,10:48-52

46.张彦,张惠文,苏振成,张成刚.长期重金属胁迫对农田土壤微生物生物量、活性和种群的影响[J].应用生态学报,2007,18(7):1491-1497

47.张彦,张惠文,苏振成,李新宇,张成刚. 清水灌溉对消除农田土壤表层镉污染的作用. 辽宁工程技术大学学报,2007, 26 (suppl.): 289-291

48.张勤,张惠文,李新宇,苏振成,张成刚. 假单胞菌质粒多样性及其在污染环境生物修复中的应用[M]. 农业生物资源与环境调控2007:307313 中国农业科学技术出版社,朱昌雄主编(第1版)。

49.张勤,张惠文,苏振成,李新宇,张成刚.长期石油和重金属污染对农田土壤假单胞菌种群多样性及结构的影响[J].应用生态学报,2007,18(6):1327-1332

50.张晶,张惠文,丛峰,张勤,李新宇,苏振成,张成刚.长期灌溉含多环芳烃污水对稻田土壤酶活性与微生物种群数量的影响[J].生态学杂志,2007,26(8):1193-1198

51.张晶,张惠文,姜勇,张成刚.清水灌溉随消除城郊稻田土壤PAHs污染的作用. 辽宁工程技术大学学报,2007,265:1-3

52.张晶,张惠文,苏振成,李新宇,张成刚.长期有机污水灌溉对土壤固氮细菌种群的影响[J].农业环境科学学报,2007,26(2):662-666

2006

53.张晶,张惠文,李新宇,苏振成,张成刚.土壤微生物生态过程与微生物功能基因多样性[J].应用生态学报,2006,17(6):1129-1132

54.张彦,张惠文,苏振成,张成刚.污水灌溉对土壤重金属含量、酶活性和微生物类群分布的影响[J].安全与环境学报,2006,6(6):44-50

55.董甜,张惠文,张粤,何兴元.长白山四种赤杨丛枝菌根真菌侵染多样性的巢式PCR-RFLP分析.[J].应用生态学报,2006,1710:1796-1800

56.熊智,唐晓萌,代玉梅,张成刚,张忠泽.徐丽华.利用rep-PCR研究云南尼泊尔杞木根瘤内Frankia基因多样性.[J]应用与环境生物学报.2006,12(5):623-627

2005

57.李新宇,张惠文,张晶,苏振成,张成刚,2005,乙草胺和甲胺磷对农田黑土可培养真菌数量及种群结构的影响,应用生态学报,166):1099-1103

58.徐明恺, 张成刚,周亚凤,张先恩. 金黄色葡萄球菌肠毒素C2的基因克隆、表达及其生物学活性,生物化学与生物物理进展2005,32(3):275-281

59.张晶,张惠文,张成刚. 实时荧光定量PCR及其在微生物生态学中的应用,生态学报,2005,25(6).1445-1450

60.郝林,张惠文,徐昕,陶思源,于龙.二氧化硫对小麦的氧化胁迫及其某些信号分子的调节.应用生态学报.2005,16(6).-1038-1042

专利

2021

1.徐明恺,张成刚,张惠文。专利名称:一种融合蛋白及其制备与应用。申请日期:20210104日,申请号:202110010261.1

2020

2.徐明恺,李婷婷,李想,李旭,张惠文。专利名称:一种微生物菌剂及其制备方法和应用。申请日期:20200923日,申请号:202011007821.X

3.徐明恺,张惠文,谷舞,张成刚。专利名称:一种畜用益生菌发酵中药饲料添加剂及其制备方法与应用。申请日期:20201209日,申请号:202011452305.8

4.张惠文,徐明恺,谷舞,张成刚。专利名称:一种禽用益生菌发酵中药饲料及其制备和应用。申请日期:20201209日,申请号:202011452307.7

2019

5.徐明恺,李永强,宋宇博,张成刚,张惠文。专利名称:超级抗原或其变体在CAR 免疫细胞制备中的应用。申请日期:20190610日,申请号:201910497894.2

6.徐明恺,宋宇博,张惠文,张成刚 。专利名称:一种融合蛋白及其制备与应用。申请日期:20190911日,申请号: 201910859687.7

7.李新宇,郭秋翠,李旭,张惠文。专利名称:一种节杆菌属细菌高密度发酵培养基。申请日期:20190409日,申请号:201910279171.5

8.李新宇,郭秋翠,李旭,张惠文。专利名称:一种改性玉米秸秆材料固定化农用微生物菌剂的制备方法。申请日期:20191114日,申请号:201911110814.X

2018

9.苏振成,班允赫,张卫建,李旭,王秀娟,王健,刘威,张惠文。专利名称:一种水稻秸秆助腐剂及其应用。申请日期:20181112日,申请号:201811338584.8

10.苏振成,班允赫,张卫建,李旭,王秀娟,王健,刘威,张惠文。专利名称:一种水稻秸秆降解菌系的扩大培养方法。申请日期:20181112日,申请号:201811338427.7

11.李新宇,李想,王欢欢,李旭, 张惠文。专利名称:一种微生物菌剂及其制备方法和应用。申请日期:20181227日, 申请号:201811608561.4

2017

12.徐明恺,宋宇博,李永强,李旭,张惠文,张成刚。专利名称:一种TrxASUMO双促溶表达标签序列及应用。申请日期:20170112日,申请号:201710022253.2

13.徐明恺,宋宇博,李永强,李旭,张惠文,张成刚。专利名称:可溶性单链抗体超抗原融合基因及蛋白和其制备与应用。申请日期:20170113日,申请号:201710024154.8

14.苏振成,李旭,班允赫。专利名称:一种以秸秆为菌源筛选秸秆降解菌系的方法及其应用。申请日期:20171110日,申请号:201711103402.4

15.张惠文,李旭,王健,苏振成。专利名称:一种烟嘧磺隆降解菌系的筛选方法及其应用。申请日期:20171129日,申请号:201711223120.8

2015

16.徐明恺,孟北乾,张惠文,张成刚。专利名称:SEC的应用及抗病毒疫苗佐剂和复合物. 申请日期:20150304日,申请号:201510095597.7

17.张惠文、杨丽强、徐明恺,苏振成、李旭、张成刚。专利名称:成刚菌属嗜甲基短杆菌及其在降解磺酰脲除草剂的应用,.申请日期:2015123日,申请号:201510881397.4授权日期:20191029日,专利号:ZL201510881397.4. 2016

18.李新宇,孙京,李旭,王萱,张惠文。专利名称:一种高效提取土壤中微生物磷脂脂肪酸的方法。申请日期:20160108日,申请号:201610012045.X

2014

19.徐明恺,邹瑾,张惠文. 专利名称:一种豆科植物根瘤固氮共生体固氮能力的快速评估方法.申请日期:20140729,申请号:201410367320.0。授权日期:2019125日,专利号:ZL201410367320.0

20.李旭,张惠文,孙健. 专利名称:一种芽孢杆菌的发酵培养方法.申请日期:20140321.申请号:201410108978.X

21.徐明恺,邹瑾,孟北乾.载体克隆表达区基因和蛋白分泌型不如动物细胞表达载体.申请日期:20140321,申请号:201410109231.6

2013

22.谢建飞,张惠文,石元亮,卢宗云,徐明恺,张成刚. 专利名称:突变改造的有机磷农药降解酶及其编码基因.申请日期:2013-2-4,申请号:201310044099.0,授权日期:20140723日,专利号:ZL201310044099.0.

23.张惠文,谢建飞,徐明恺,张成刚,石元亮,卢宗云. 专利名称:随机突变改造的有机磷农药降解酶及其编码基因.申请日期:2013-2-4,申请号:201310044547.7,授权日期:20140514日,专利号:ZL201310044547.7

24.谢建飞,张惠文,石元亮,卢宗云. 专利名称:一种随机突变改造的有机磷农药降解酶及其编码基因.申请日期:2013-2-4,申请号:201310043314.5

25.张惠文,谢建飞,徐明恺,张成刚,石元亮,卢宗云. 专利名称:一种有机磷农药降解酶活力检测方法.申请日期:2013-2-4,申请号:201310043315.X;

26.张惠文,王硕,徐明恺. 专利名称:一种从酵母菌体中纯化还原型谷胱甘肽的方法.申请日期:2013110,申请号:201310010072.X;

27.张惠文,李旭,孙健,苏振成,李新宇. 专利名称: 一种抑制植物病虫害的微生物菌剂及其制备方法和应用.申请日期:2013625日,申请号:201310258060.9

2012

28.苏振成,谢跃武,王硕,孙健,王秀娟,赵继阳,张惠文. 专利名称:半自动微胶囊成型装置.申请日期:2012-8-17,申请号:201210295457.0;授权日期:20140723日,专利号:ZL 201210295457.0.

2011

29.徐明恺,王洪波,谭焕波. 专利名称:抗原性改变的肠毒素C2突变体及编码基因与制备和应用.申请日期:2011-2-15,申请号:2011110041499.7

30.张惠文,王洪波,徐明恺. 专利名称:活性增强的SEC2突变蛋白及编码基因与制备和应用.申请日期:2011-3-30, 申请号:201110077088.3。授权日期:20141022日,专利号:ZL201110077088.3           

31.张惠文,李旭,张成刚,苏振成,李新宇,徐明恺. 专利名称:一种微生物菌剂及其制备方法和应用.申请日期:2011-11-29,申请号:201110387181.4授权日期:20160330日,专利号:ZL 201110387181.4.

2010

32.张惠文,李旭,苏振成,王秀娟,孙健,张成刚。专利名称:一种微生物菌剂及其制备方法和应用.申请日期:20101115日,申请号:201010543419.3。授权日期:20150415日,专利号:ZL201010543419.3

33.张惠文,李旭,苏振成.专利名称:一种固定化磷细菌肥料及其制备方法.申请日期:20101125日,申请号:201010559057.5

34.苏振成,胡凤钗,李新宇,王秀娟,张惠文. 专利名称:一种以多环芳烃为底物的降解菌的筛选方法.申请日期:2010-12-15, 申请号:201010588933.9

2009

35.许思明.专利名称:一种玫瑰口腔消毒液及其制备方法 申请日期:2005126日,申请号:200510047928.6.授权日期:200978日,专利号:ZL 200510047928.6

36.张惠文,张晓黎,阮晓东,李旭,李新宇,苏振成.专利名称:一种制备防治大豆根腐病的复合菌剂的方法.申请日期:2009325日,申请号:200910010876.3

37.张惠文,张晓黎,蔡颖慧,李旭,李新宇,苏振成.专利名称:一种以氯嘧磺隆为底物的混菌降解菌剂的筛选方法.申请日期:2009325日,申请号:200910010877.8

38.张惠文 蔡颖慧 苏振成 李旭 李新宇.专利名称:一种快速检测有机磷降解菌降解率的分析方法. 申请日期:2009213日,申请号:200910300399.4

2008

39.徐明恺,张惠文,张成刚. 专利名称:一种原核表达载体pASK-75-EX.申请日期:2005330日,申请号:200510046140.3.授权日期:200819.专利号:ZL 2005 1 0046140.3.

40.张惠文,王秀娟,李旭,苏振成,张晓黎,张成刚。专利名称:一种以高效氯氟氰菊酯为底物的降解菌株的筛选方法,申请日期:2008319日,申请号:200810010695.6.,授权日期:2011914日,专利号:ZL200810010695.6

41.张惠文,阮晓东,李旭,苏振成.专利名称:一种用食用菌菌糠制备花土的方法.申请日期:2008326日,申请号:200810010761.X

42.张惠文,阮晓东,张晓黎,蔡颖慧,苏振成.专利名称:一种食用菌液体菌种静息化保存方法.申请日期:200842日,申请号:200810010886.2.授权日期:20101013日,专利号:ZL 2008 1 0010886.2

43.王小刚, 张惠文, 徐明恺, 张成刚.专利名称:一种超抗原活性增强的SEC2突变基因及其制备方法. 申请日期:200866日,申请号: 200810011709.6,授权日期:2011511日,专利号:ZL200810011709.6

44.张惠文,蔡颖慧,张晓黎,苏振成,李旭.专利名称:一株以敌敌畏为底物的降解菌株的筛选方法 ;申请日期:200866日,申请号:200810011713.2。授权日期:2013227日,专利号:ZL 200810011713.2

45.张惠文 阮晓东 李旭 苏振成. 专利名称:一种液固双相发酵生产小克银汉霉孢子的方法.申请日期:2008425日,申请号: 200810011185.0,授权日期:2011119日,专利号:ZL200810011185.0

46.张惠文 阮晓东 张晓黎 罗永平 苏振成.专利名称:一种木霉孢子菌剂及其制备方法. 申请日期:2008425日,申请号:200810011186.5,授权日期:2011420日,专利号:ZL 200810011186.5

47.张惠文,蔡颖慧,苏振成,李旭,阮晓东.专利名称:一种有机磷降解制剂及其制备方法 ;申请日期:2008730日,申请号200810012565.6

48.张惠文 阮晓东 蔡颖慧 张晓黎 李旭 苏振成.专利名称:一种用于染料废水脱色的改性菌糠吸附剂的制备方法. 申请日期:2008117日,申请号:200810228635.1,授权日期:201373日,专利号:ZL20081022835.1

49.张惠文 阮晓东 李新宇 蔡颖慧 李旭 苏振成. 专利名称:一种采用固定化真菌菌体对印染废水脱色的方法. 申请日期:2008117日,申请号:200810228636.6

50.张惠文,蔡颖慧,苏振成,李旭:专利名称:一种有机磷降解酶制剂及其制备方法.申请日期:20081114日,申请号:200810228798.x

2007

51.张惠文,张成刚,李旭,苏振成,吕英杰,专利名称:一种红树莓保健酒及其酿造方法,申请日期:2007413日,申请号:200710010958.9。授权日期:2012111日,专利号:ZL200710010958.9

52.李旭,张惠文,张成刚,苏振成,李新宇,专利名称:一种红树莓专用微生物有机复合肥料及其制备方法,申请日期:2007413日,申请号:200710010959.3。授权日期:2010915日,专利号:ZL 2007 1 0010959.3

53.张惠文,张成刚,李旭,苏振成,吕英杰,专利名称:一种红树莓酒的酿造方法及其应用;申请日期:2007413日,申请号:200710010960.6。授权日期:2011119号,专利号:ZL200710010960.6

54.张惠文,张晓黎,苏振成,李旭,张成刚,专利名称:一种苄嘧磺隆高效降解菌株的筛选及其降解活性的鉴定方法,申请日期:2007620日,申请号:200710011800.3

55.苏振成,张惠文,李新宇,吴敏娜,张成刚.专利名称:一种土壤微生物基因组DNA提取方法,申请日期:2007822日,申请号:200710012539.9。授权日期:201274日,专利号:ZL200710012539.9

56.李旭,张惠文,苏振成,张成刚,专利名称:一种枯草芽孢杆菌脂肽类抗菌物质的分离提取方法,申请日期:2007822日,申请号:200710012540.1

57.张惠文,吕英杰,李旭,张成刚,专利名称:一种红树莓保健饮料及其制备方法,申请日期:2007831日,申请号:200710012654.6

58.苏振成,张惠文,李旭,李新宇,张成刚,专利名称:一种简易高效的PCR产物纯化回收方法及其专用装置,申请日期:2007831日,申请号:200710012655.0

59.张惠文,罗永平,王小刚,苏振成,张成刚,专利名称:一种抗菌肽基因及其制备方法和该基因在毕赤酵母载体中的表达质粒的构建,申请日期:2007921日,申请号:200710012919.2

60.张惠文,吴敏娜,李旭,李新宇,苏振成,张成刚,专利名称:一种土壤真菌拮抗模型的构建方法,申请日期:20071019日,申请号:200710057564.6

61.张成刚,王小刚,徐明恺,张惠文,苏振成,专利名称:肠毒素C2超抗原突变蛋白基因的克隆和异源表达方法,申请日期:20071031日,申请号:200710157854.0

62.苏振成,张惠文,李新宇,李旭,张成刚,专利名称:一种有机芳香化合物降解菌及其应用,申请日期:2007112日,申请号:200710157904.5

63.苏振成,张惠文,李新宇,李旭,张成刚,专利名称:一种多环芳烃降解菌剂的制备方法,申请日期:2007112日,申请号:200710157905.x,授权日期:2010128日,专利号:  ZL200710157905.X

64.徐明恺,张惠文,张成刚,王小刚,专利名称:一种肠毒素C2蛋白的制备方法,申请日期:20071212日,申请号:200710158820.3 

65.徐明恺,张惠文,张成刚,王小刚,专利名称:融合免疫毒素B-L-Vpr基因及克隆和异源表达方法,申请日期:20071219日,申请号:200710159021.8

66.张惠文,许思明,专利名称:一种玫瑰花超细粉体制备方法,申请日期:20071221日,申请号:200710159106.6

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